The Antidiabetic Effect of Lupine Turmos Compared With Antidiabetic Drug (Glibenclamide)
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Polymeric Microparticles as Alternative Carriers for Antidiabetic Glibenclamide Drug
Background: Glibenclamide is a lipophilic drug widely used in type 2 diabetes treatment. However, its low bioavailability limits its use. Thus, novel formulations should be applied to improve the drug’s bioavailability. Objectives: This study aimed to develop alternative carriers for oral delivery of glibenclamide. For this purpose, two biocompatible polymers, poly(e-caprolactone) and poly(but...
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context: over the last few decades, extensive efforts have been made worldwide to develop nanomedicine delivery systems, especially via oral route for antidiabetic drugs. absorption of insulin is hindered by epithelial cells of gastrointestinal tract, acidic gastric ph and digestive enzymes. evidence acquisition: recent reports have identified and explained the beneficial role of several struct...
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ژورنال
عنوان ژورنال: Diabetes & its Complications
سال: 2018
ISSN: 2639-9326
DOI: 10.33425/2639-9326.1022